Template:PBB/6714

V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
PDB rendering based on 1a07.
PDBに登録されている構造
PDB Ortholog search: PDBe, RCSB, PDBj
PDBのIDコード一覧

1A07​, 1A08​, 1A09​, 1A1A​, 1A1B​, 1A1C​, 1A1E​, 1FMK​, 1HCS​, 1HCT​, 1KSW​, 1O41​, 1O42​, 1O43​, 1O44​, 1O45​, 1O46​, 1O47​, 1O48​, 1O49​, 1O4A​, 1O4B​, 1O4C​, 1O4D​, 1O4E​, 1O4F​, 1O4G​, 1O4H​, 1O4I​, 1O4J​, 1O4K​, 1O4L​, 1O4M​, 1O4N​, 1O4O​, 1O4P​, 1O4Q​, 1O4R​, 1SHD​, 1Y57​, 1YI6​, 1YOJ​, 1YOL​, 1YOM​, 2BDF​, 2BDJ​, 2H8H​, 2SRC​, 3VRO​, 4F59​, 4F5A​, 4F5B​, 4HXJ

識別記号
記号 SRC; ASV; SRC1; c-SRC; p60-Src
その他ID OMIM190090 MGI英語版98397 HomoloGene英語版21120 ChEMBL: 267 GeneCards: SRC Gene
EC番号 2.7.10.2
遺伝子オントロジー
分子機能 protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
SH3/SH2 adaptor activity
receptor binding
integrin binding
protein binding
ATP binding
kinase activity
heme binding
SH2 domain binding
identical protein binding
ion channel binding
ephrin receptor binding
phosphoprotein binding
細胞の構成要素 nucleus
cytoplasm
mitochondrial inner membrane
lysosome
late endosome
cytosol
cytoskeleton
plasma membrane
caveola
生物学的プロセス cell cycle
cell adhesion
signal transduction
signal complex assembly
epidermal growth factor receptor signaling pathway
intracellular protein kinase cascade
Ras protein signal transduction
axon guidance
blood coagulation
fibroblast growth factor receptor signaling pathway
cellular membrane organization
peptidyl-tyrosine phosphorylation
virus-host interaction
platelet activation
forebrain development
T cell costimulation
negative regulation of protein homooligomerization
regulation of intracellular estrogen receptor signaling pathway
positive regulation of integrin activation
Fc-gamma receptor signaling pathway involved in phagocytosis
regulation of vascular permeability
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
innate immune response
regulation of bone resorption
bone resorption
protein autophosphorylation
neurotrophin TRK receptor signaling pathway
oogenesis
progesterone receptor signaling pathway
leukocyte migration
negative regulation of focal adhesion assembly
positive regulation of protein kinase B signaling cascade
uterus development
branching involved in mammary gland duct morphogenesis
positive regulation of ERK1 and ERK2 cascade
response to interleukin-1
cellular response to progesterone stimulus
positive regulation of podosome assembly
positive regulation of canonical Wnt receptor signaling pathway
negative regulation of anoikis
negative regulation of extrinsic apoptotic signaling pathway
negative regulation of intrinsic apoptotic signaling pathway
出典: Amigo / EGO
RNA発現パターン
その他参照発現データ
オルソログ
ヒト マウス
Entrez英語版 6714 20779
Ensembl英語版 ENSG00000197122 ENSMUSG00000027646
UniProt英語版 P12931 P05480
RefSeq (mRNA) NM_005417 NM_001025395
RefSeq (protein) NP_005408 NP_001020566
Location (UCSC) Chr 20:
35.97 - 36.03 Mb
Chr 2:
157.42 - 157.47 Mb
PubMed search [1] [2]
KEGG GENES hsa:6714 mmu:20779