プロトカテク酸エチル

出典: フリー百科事典『ウィキペディア(Wikipedia)』
移動: 案内検索
プロトカテク酸エチル[1]
識別情報
CAS登録番号 3943-89-3
PubChem 77547
ChemSpider 69954
EINECS 223-529-0
特性
化学式 C9H10O4
モル質量 182.17 g/mol
精密質量 182.057909 u
外観 White or pale brownish yellow, crystalline powder; odourless or has a faint

phenol-like odour

融点

132-135°C

沸点

357-358°C[2]

への溶解度 Insoluble in water; soluble in ethanol
特記なき場合、データは常温 (25 °C)・常圧 (100 kPa) におけるものである。

プロトカテク酸エチル(ethyl protocatechuate)はフェノール類の一つ。プロトカテク酸のエチルエステルである。落花生種子種皮で見られ[3][4]ワインにも含まれる[5]

プロリル 4-ヒドロキシラーゼ阻害剤であり[6]心筋の保護に使われる[7]

出典[編集]

  1. ^ Ethyl protocatechuate on FAO website
  2. ^ Ethyl protocatechuate on www.thegoodscentscompany.com
  3. ^ Identification of an Antioxidant, Ethyl Protocatechuate, in Peanut Seed Testa. Shiow Chyn Huang, Gow-Chin Yen, Lee-Wen Chang, Wen-Jye Yen and Pin-Der Duh, J. Agric. Food Chem., 2003, 51 (8), pages 2380–2383, PMID: 12670184, doi:10.1021/jf0210019
  4. ^ Antioxidant activity of peanut seed testa and its antioxidative component, ethyl protocatechuate. Wen-Jye Yen, Lee-Wen Chang, Pin-Der Duh, LWT - Food Science and Technology, Volume 38, Issue 3, May 2005, pages 193-200, doi:10.1016/j.lwt.2004.06.004
  5. ^ Isolation and Characterization of Novel Benzoates, Cinnamates, Flavonoids, and Lignans from Riesling Wine and Screening for Antioxidant Activity. Beate Baderschneider and Peter Winterhalter, J. Agric. Food Chem., 2001, 49 (6), pages 2788–2798, doi:10.1021/jf010396d
  6. ^ The prolyl 4-hydroxylase inhibitor ethyl-3,4-dihydroxybenzoate generates effective iron deficiency in cultured cells. Wang J, Buss JL, Chen G, Ponka P and Pantopoulos K, FEBS Lett., 2002 Oct 9, 529(2-3), pages 309-312, PMID: 12372619, doi:10.1016/S0014-5793(02)03389-6
  7. ^ Desferoxamine and ethyl-3,4-dihydroxybenzoate protect myocardium by activating NOS and generating mitochondrial ROS. Philipp S, Cui L, Ludolph B, Kelm M, Schulz R, Cohen MV and Downey JM, Am J Physiol Heart Circ Physiol., 2006 Jan, 290(1), H450-457, PMID: 16155105, doi:10.​1152/​ajpheart.​00472.​2005

関連項目[編集]